The shape of nearly every protein!

YouCanCallMeAl
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The shape of nearly every protein!

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https://www.sciencealert.com/ai-predict ... to-science

What is a protein anyway? Does it even exist?
Linked together in chains, these amino acid sequences spool long proteins that are folded into pleated sheets and twisting ribbons.

By understanding the shape which any given protein folds into, scientists can get a grip on how that protein operates, deciphering what its main role is inside cells.
Apparently it does, and it takes up long complicated shapes, a bit like dna.
Already, researchers have used AlphaFold's first batch of predictions to refine their understanding of deadly diseases such as malaria, opening the door to improved vaccines, and to deciphering biological puzzles about behemoth proteins that have stumped scientists for decades.

Not to mention identifying never-seen-before enzymes that could help up-cycle plastic pollution.
Good for vaccines and plastic pollution. This tech has a future!
"In the past year alone, there have been over a thousand scientific articles on a broad range of research topics which use AlphaFold structures; I have never seen anything like it.

"And this is just the impact of 1 million predictions," Velankar added. "Imagine the impact of having over 200 million protein structure predictions openly accessible in the AlphaFold database."
Soooo many articles!
"According to EMBL-EBI, around one-third of the more than 214 million predictions have been classed as highly accurate, on par with protein structures derived from the usual experimental methods, such as X-ray crystallography and cryo-electron microscopy."
One third of the structures are as accurate as X-ray crystallography and cryo-electron microscopy.. And just how accurate is that?

I think it's just models of models. Meta-modelling. But all these models do represent the underlying reality, right? Right?!? Sure they do.
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